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Article

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block.

Journal of the American Heart Association - 20 May 2016

Syam Ninda, Chatel Stéphanie, Ozhathil Lijo Cherian, Sottas Valentin, Rougier Jean-Sébastien, Baruteau Alban, Baron Estelle, Amarouch Mohamed-Yassine, Daumy Xavier, Probst Vincent, Schott Jean-Jacques, Abriel Hugues

Abstract excerpt

BACKGROUND: Transient receptor potential melastatin member 4 (TRPM4) is a nonselective cation channel. TRPM4 mutations have been linked to cardiac conduction disease and Brugada syndrome. The mechanisms underlying TRPM4-dependent conduction slowing are not fully understood. The aim of this study was to characterize TRPM4 genetic variants found in patients with congenital or childhood atrioventricular block....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27207958
DOI: 10.1161/JAHA.114.001625
PMCID: PMC4889160

Genes

TRPM4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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