Article
Mitochondrial dysfunction in neurodegenerative diseases and cancer.
Environmental and molecular mutagenesis - 1 Jun 2010
de Moura Michelle Barbi, dos Santos Lucas Santana, Van Houten Bennett
Abstract excerpt
Mitochondria are important integrators of cellular function and therefore affect the homeostatic balance of the cell. Besides their important role in producing adenosine triphosphate through oxidative phosphorylation, mitochondria are involved in the control of cytosolic calcium concentration, metabolism of key cellular intermediates, and Fe/S cluster biogenesis and contributed to programmed cell death....
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