[Effects of wild-type PTEN overexpression and its mutation on F-actin in activated hepatic stellate cells].

doi:10.3760/cma.j.issn.1007-3418.2017.01.006

Article

[Effects of wild-type PTEN overexpression and its mutation on F-actin in activated hepatic stellate cells].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 20 Jan 2017

Hao L S, Liu Y L, Zhang G L, Chen J, Song X J, Wang Y L, Wang J, Jin L M

Abstract excerpt

Objective: To investigate the effect of overexpression of wild-type phosphatase and tensin homolog (PTEN) deleted on chromosome 10 and its mutant G129E (exhibiting the activity of protein phosphatase and losing the activity of lipid phosphatase) on F-actin in activated hepatic stellate cells (HSCs) cultured in vitro. Methods: The activated hepatic stellate cell-T6 (HSC-T6) cells were cultured in vitro, and...

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[Effects of wild-type PTEN overexpression and its mutation on F-actin in activated hepatic stellate cells].

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