Article
Human Lung Spheroids as In Vitro Niches of Lung Progenitor Cells with Distinctive Paracrine and Plasticity Properties.
Stem cells translational medicine - 1 Mar 2017
Chimenti Isotta, Pagano Francesca, Angelini Francesco, Siciliano Camilla, Mangino Giorgio, Picchio Vittorio, De Falco Elena, Peruzzi Mariangela, Carnevale Roberto, Ibrahim Mohsen, Biondi-Zoccai Giuseppe, Messina Elisa, Frati Giacomo
Abstract excerpt
Basic and translational research on lung biology has discovered multiple progenitor cell types, specialized or facultative, responsible for turnover, renewal, and repair. Isolation of populations of resident lung progenitor cells (LPCs) has been described by multiple protocols, and some have been successfully applied to healthy human lung tissue. We aimed at understanding how different cell culture conditions may...
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