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Article

Frequent coinfection of cells explains functional in vivo complementation between cytomegalovirus variants in the multiply infected host.

Journal of virology - 1 Aug 2005

Cicin-Sain Luka, Podlech Jürgen, Messerle Martin, Reddehase Matthias J, Koszinowski Ulrich H

Abstract excerpt

In contrast to many other virus infections, primary cytomegalovirus (CMV) infection does not fully protect against reinfection. Accordingly, clinical data have revealed a coexistence of multiple human CMV variants/strains in individual patients. Notably, the phenomenon of multiple infection was found to correlate with increased virus load and severity of CMV disease. Although of obvious medical relevance, the...

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Identifiers

PMID: 16014912
DOI: 10.1128/JVI.79.15.9492-9502.2005
PMCID: PMC1181553

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Source receipt: pubmed, retrieved 7 Sept 2026.

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