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A 3D Cell Death Assay to Quantitatively Determine Ferroptosis in Spheroids

13 Mar 2020

Abstract excerpt

The failure of drug efficacy in clinical trials remains a big issue in cancer research. This is largely due to the limitations of two-dimensional (2D) cell cultures, the most used tool in drug screening. Nowadays, three-dimensional (3D) cultures, including spheroids, are acknowledged to be a better model of the in vivo environment, but detailed cell death assays for 3D cultures (including those for ferroptosis)...

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PMID: 32183000
DOI: 10.3390/cells9030703

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