Article
Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplantation.
Journal of immunology research - 1 Jan 2017
Geneugelijk Kirsten, Wissing Jeroen, Koppenaal Dirk, Niemann Matthias, Spierings Eric
Abstract excerpt
Epitope-based HLA matching has been emerged over the last few years as an improved method for HLA matching in solid organ transplantation. The epitope-based matching concept has been incorporated in both the PIRCHE-II and the HLAMatchmaker algorithm to find the most suitable donor for a recipient. For these algorithms, high-resolution HLA genotype data of both donor and recipient is required. Since...
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