Article
Integration site selection by retroviruses and transposable elements in eukaryotes.
Nature reviews. Genetics - 1 May 2017
Sultana Tania, Zamborlini Alessia, Cristofari Gael, Lesage Pascale
Abstract excerpt
Transposable elements and retroviruses are found in most genomes, can be pathogenic and are widely used as gene-delivery and functional genomics tools. Exploring whether these genetic elements target specific genomic sites for integration and how this preference is achieved is crucial to our understanding of genome evolution, somatic genome plasticity in cancer and ageing, host-parasite interactions and genome...
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