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Article

Mutagen resistance and mutation restriction of St. Louis encephalitis virus.

The Journal of general virology - 1 Feb 2017

Griesemer Sara B, Kramer Laura D, Van Slyke Greta A, Pata Janice D, Gohara David W, Cameron Craig E, Ciota Alexander T

Abstract excerpt

The error rate of the RNA-dependent RNA polymerase (RdRp) of RNA viruses is important in maintaining genetic diversity for viral adaptation and fitness. Numerous studies have shown that mutagen-resistant RNA virus variants display amino acid mutations in the RdRp and other replicase subunits, which in turn exhibit an altered fidelity phenotype affecting viral fitness, adaptability and pathogenicity. St. Louis...

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Identifiers

PMID: 28284278
DOI: 10.1099/jgv.0.000682
PMCID: PMC6537618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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