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Article

Super folds, networks, and barriers.

Proteins - 1 Feb 2012

Burke Sean, Elber Ron

Abstract excerpt

Exhaustive enumeration of sequences and folds is conducted for a simple lattice model of conformations, sequences, and energies. Examination of all foldable sequences and their nearest connected neighbors (sequences that differ by no more than a point mutation) illustrates the following: (i) There exist unusually large number of sequences that fold into a few structures (super-folds). The same observation was...

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Identifiers

PMID: 22095563
DOI: 10.1002/prot.23212
PMCID: PMC3290721

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