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Article

Measurement of NET formation in vitro and in vivo by flow cytometry

17 Jul 2017

Abstract excerpt

Neutrophil extracellular traps (NETs) are extracellular chromatin fibers adorned with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. NETosis is the metamorphosis of neutrophils with NET formation that follows decondensation of DNA and rupture of the plasma membrane. Although NETs play important roles in innate immunity, excessive formation of NETs can be...

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PMID: 28715618
DOI: 10.1002/cyto.a.23169

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