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Article

TUSC3: a novel tumour suppressor gene and its functional implications.

Journal of cellular and molecular medicine - 1 Sept 2017

Yu Xinshuang, Zhai Chunjuan, Fan Yujun, Zhang Jiandong, Liang Ning, Liu Fengjun, Cao Lili, Wang Jia, Du Juan

Abstract excerpt

The tumour suppressor candidate 3 (TUSC3) gene is located on chromosome region 8p22 and encodes the 34 kD TUSC3 protein, which is a subunit of the oligosaccharyl transferase responsible for the N-glycosylation of nascent proteins. Known to be related to autosomal recessive mental retardation for several years, TUSC3 has only recently been identified as a potential tumour suppressor gene. Based on the structure...

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Identifiers

PMID: 28272772
DOI: 10.1111/jcmm.13128
PMCID: PMC5571513

Genes

TUSC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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