Article
Epistasis in Neuropsychiatric Disorders.
Trends in genetics : TIG - 1 Apr 2017
Webber Caleb
Abstract excerpt
The contribution of epistasis to human disease remains unclear. However, several studies have now identified epistatic interactions between common variants that increase the risk of a neuropsychiatric disorder, while there is growing evidence that genetic interactions contribute to the pathogenicity of rare, multigenic copy-number variants (CNVs) that have been observed in patients. This review discusses the...
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