Article
MCR-1.6, a New MCR Variant Carried by an IncP Plasmid in a Colistin-Resistant Salmonella enterica Serovar Typhimurium Isolate from a Healthy Individual.
Antimicrobial agents and chemotherapy - 1 May 2017
Lu Xin, Hu Yongfei, Luo Ming, Zhou Haijian, Wang Xiaoxun, Du Yu, Li Zhenpeng, Xu Jialiang, Zhu Baoli, Xu Xuebin, Kan Biao
Abstract excerpt
In this study, we report a novel mcr-1 gene variant, named mcr-1.6, carried by an IncP plasmid in a colistin-resistant Salmonella enterica serovar Typhimurium isolate from a healthy person. Compared with mcr-1, the mcr-1.6 gene contains two single-nucleotide polymorphisms, one of which results in an arginine to histidine variation (Arg536→His). The plasmid carrying the mcr-1.6 gene was designated pMCR1.6_P053 and...
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