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Article

Emergence of coexisting blaNDM and mcr-1 genes in Escherichia coli isolates from the guts of healthy individuals.

Microbiology spectrum - 3 Feb 2026

Wang Shuang, Liu Lu, Du Lei, Gao Shanli, Yu Xiaolin, Cheng Lixiao, Chen Yuzhen, Kou Zengqiang, Sun Wenkui

Abstract excerpt

The emergence of blaNDM/mcr-1-positive Escherichia coli poses a huge challenge to infection control. The purpose of this study was to investigate the plasmid and genomic characteristics of blaNDM/mcr-1-positive E. coli isolates from the gut of healthy individuals. This study performed drug susceptibility testing, whole-genome sequencing (WGS), analysis of resistance genes, characterization of plasmids, and...

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Identifiers

PMID: 41432552
DOI: 10.1128/spectrum.02014-25
PMCID: PMC12889101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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