Article
mcr-1.2, a New mcr Variant Carried on a Transferable Plasmid from a Colistin-Resistant KPC Carbapenemase-Producing Klebsiella pneumoniae Strain of Sequence Type 512.
Antimicrobial agents and chemotherapy - 1 Sept 2016
Di Pilato Vincenzo, Arena Fabio, Tascini Carlo, Cannatelli Antonio, Henrici De Angelis Lucia, Fortunato Simona, Giani Tommaso, Menichetti Francesco, Rossolini Gian Maria
Abstract excerpt
A novel mcr variant, named mcr-1.2, encoding a Gln3-to-Leu functional variant of MCR-1, was detected in a KPC-3-producing ST512 Klebsiella pneumoniae isolate collected in Italy from a surveillance rectal swab from a leukemic child. The mcr-1.2 gene was carried on a transferable IncX4 plasmid whose structure was very similar to that of mcr-1-bearing plasmids previously found in Escherichia coli and K. pneumoniae...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.