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Article

Neutron activation increases activity of ruthenium-based complexes and induces cell death in glioma cells independent of p53 tumor suppressor gene.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine - 1 Apr 2017

Montel Aline Monezi, Dos Santos Raquel Gouvêa, da Costa Pryscila Rodrigues, Silveira-Lacerda Elisângela de Paula, Batista Alzir Azevedo, Dos Santos Wagner Gouvêa

Abstract excerpt

Novel metal complexes have received great attention in the last decades due to their potential anticancer activity. Notably, ruthenium-based complexes have emerged as good alternative to the currently used platinum-based drugs for cancer therapy, providing less toxicity and side effects to patients. Glioblastoma is an aggressive and invasive type of brain tumor and despite of advances is the field of...

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Identifiers

PMID: 28258507
DOI: 10.1007/s10534-017-0006-1
PMCID: PMC5352776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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