Article
Association of IL10, IL4, IFNG, and CTLA4 Gene Polymorphisms with Efavirenz Hypersensitivity Reaction in Patients Infected with Human Immunodeficiency Virus.
Japanese journal of infectious diseases - 24 Jul 2017
de Oliveira Rodrigues Raphael, Helena Barem Rabenhorst Silvia, Germano de Carvalho Paulo, Luri Sasahara Greyce, Mabel Ferreira Vasconcelos Luciana, Antônio Gomes de Arruda Érico, Fernandes Ribeiro da Silva Silvia, Farias Ribeiro Ilana, Tiemi Nagao-Dias Aparecida
Abstract excerpt
We evaluated interleukin-10 (IL10) －592 C/A, IL4－589 C/T, interferon gamma (IFNG)＋874 A/T, cytotoxic T-lymphocyte-associated antigen 4 (CTLA4)＋49 A/G gene polymorphisms associated with efavirenz hypersensitivity reaction. A total of 63 human immunodeficiency virus-positive patients under treatment at a public hospital were included in the study, of whom 21 presented with efavirenz hypersensitivity. Patients who...
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