Article
Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among intravenous drug users.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2015
Kallas Eveli, Huik Kristi, Pauskar Merit, Jõgeda Ene-Ly, Karki Tõnis, Des Jarlais Don, Uusküla Anneli, Avi Radko, Lutsar Irja
Abstract excerpt
BACKGROUND: Interleukin 10 (IL-10) is a multifunctional cytokine produced by macrophages, monocytes, and T-helper cells. Two polymorphisms at positions -592 and -1082 have been associated with HIV susceptibility. However, their associations with susceptibility to HIV and its co-infections among intravenous drug users (IDUs) are largely unknown. METHODS: A total of 345 IDUs were recruited. Of the 173 HIV negative...
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