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Article

Association of IL-4 and IL-10 gene promoter polymorphisms with common variable immunodeficiency.

Immunobiology - 1 Jan 2010

Rezaei Nima, Aghamohammadi Asghar, Mahmoudi Mahdi, Shakiba Yadollah, Kardar Gholam Ali, Mahmoudi Maryam, Moradi Batoul, Amirzargar Ali Akbar

Abstract excerpt

Common variable immunodeficiency (CVID) is a heterogeneous group of disorders, characterized by severe reduction in serum IgG and IgA with normal or low number of B-cells. Interleukin (IL)-4 and IL-10 levels could be altered in CVID patients, while cytokine production could be affected with polymorphisms of gene promoter regions. The allele and genotype frequencies of IL-4 and IL-10 gene promoter polymorphic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19249119
DOI: 10.1016/j.imbio.2009.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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