Article
Immunophenotypic Shifts in Primary Cutaneous γδ T-Cell Lymphoma Suggest Antigenic Modulation: A Study of Sequential Biopsy Specimens.
The American journal of surgical pathology - 1 Apr 2017
Agbay Rose Lou Marie C, Torres-Cabala Carlos A, Patel Keyur P, Merril Eric D, Duvic Madeleine, Quesada Andres, Prieto Victor G, Aung Phyu P, Loghavi Sanam, Young Ken H, Hu Shimin, Ferrufino-Schmidt Maria C, Tetzlaff Michael, Li Shaoying, Medeiros L Jeffrey, Miranda Roberto N
Abstract excerpt
Primary cutaneous γδ T-cell lymphoma (PCGD TCL), an aggressive type of lymphoma, accounts for approximately 1% of all primary cutaneous lymphomas. We have occasionally observed changes in T-cell antigen expression (immunophenotypic [IP] shift) over time, a phenomenon that is considered rare in T-cell lymphoma including cutaneous T-cell lymphoma. Therefore, we assessed sequential biopsies of PCGD TCL for possible...
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