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Article

Phenotypic Variability in Primary Cutaneous Anaplastic Large T-cell Lymphoma

6 Jan 2014

Abstract excerpt

Primary cutaneous anaplastic large T-cell lymphoma (pcALCL) is a well-defined entity characterized by neoplastic cells expressing CD30, CD2, CD3, CD4, and CD5. Cases with different phenotype have been reported, including variable loss of CD2, CD3, and CD5, and expression of cytotoxic phenotype (CD8⁺) and/or of cytotoxic proteins. Aberrant phenotypes represent a diagnostic pitfall and may be the cause of...

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PMID: 24394302
DOI: 10.1097/dad.0b013e3182a5683a

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