Article
Immunophenotypic switch in cutaneous T-cell lymphoma: A series of three cases and review of the literature.
Journal of cutaneous pathology - 1 Jul 2021
Bitar Carole, Hile Grace, Brown Noah A, Fullen Douglas R, Lowe Lori, Tejasvi Trilokraj, Wilcox Ryan A, Harms Paul W, Chan May P, Bresler Scott C, Hristov Alexandra C
Abstract excerpt
Primary cutaneous T-cell lymphoma (CTCL) comprises a heterogeneous group of neoplasms with variable clinical behavior. Immunophenotypic switch (IS) is a phenomenon that occurs during lymphoma progression and is defined by an alteration in the immunophenotypic expression of a tumor with retention of its genotypic signature. This has been well-recognized in hematopoietic neoplasms; however, it has been rarely...
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