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Article

Influence of CYP2C192/17 genotype on adverse drug reactions of voriconazole in patients after allo-HSCT: a four-case report.

Journal of cancer research and clinical oncology - 1 Jun 2017

Beata Sienkiewicz, Donata Urbaniak-Kujda, Jarosław Dybko, Tomasz Wróbel, Anna Wiela-Hojeńska

Abstract excerpt

PURPOSE: Voriconazole (VCZ) is a new-generation triazol antifungal agent. CYP2C19 mutations have been reported to cause variability in VCZ pharmacokinetics, and thus lead to undesirable effects of pharmacotherapy. We observed four Caucasian patients who underwent allogenic hematopoietic stem cell transplantation, treated with voriconazole for prevention of fungal infections, to establish the impact of...

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Share to Cytochrome P-450 CYP2C19
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

Share to Leukemia, Myeloid, Acute

Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 28247033
DOI: 10.1007/s00432-017-2357-y
PMCID: PMC5427156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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