Article
APOH interacts with FTO to predispose to healthy thinness.
Human genetics - 1 Feb 2016
Hasstedt Sandra J, Coon Hilary, Xin Yuanpei, Adams Ted D, Hunt Steven C
Abstract excerpt
We identified eight candidate thinness predisposition variants from the Illumina HumanExome chip genotyped on members of pedigrees selected for either healthy thinness or severe obesity. For validation, we tested the candidates for association with healthy thinness in additional pedigree members while accounting for effects of obesity-associated genes: NPFFR2, NPY2R, FTO, and MC4R. Significance was obtained for...
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