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Article

Immune profiles of elderly breast cancer patients are altered by chemotherapy and relate to clinical frailty.

Breast cancer research : BCR - 28 Feb 2017

Bailur Jithendra Kini, Pawelec Graham, Hatse Sigrid, Brouwers Barbara, Smeets Ann, Neven Patrick, Laenen Annouschka, Wildiers Hans, Shipp Christopher

Abstract excerpt

BACKGROUND: Effective therapeutic management of elderly patients with cancer, on an individual basis, remains a clinical challenge. Here, we identify novel biomarkers to assess elderly patients (≥70 years of age) with breast cancer undergoing treatment with or without chemotherapy. METHODS: We performed comprehensive geriatric assessment and measured markers sensitive to alteration in ageing, including leukocyte...

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Identifiers

PMID: 28241844
DOI: 10.1186/s13058-017-0813-x
PMCID: PMC5330012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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