Article
The DARC Side of Inflamm-Aging: Duffy Antigen Receptor for Chemokines (DARC/ACKR1) as a Potential Biomarker of Aging, Immunosenescence, and Breast Oncogenesis among High-Risk Subpopulations.
Cells - 29 Nov 2022
Jinna Nikita, Rida Padmashree, Su Tianyi, Gong Zhihong, Yao Song, LaBarge Mark, Natarajan Rama, Jovanovic-Talisman Tijana, Ambrosone Christine, Seewaldt Victoria
Abstract excerpt
The proclivity of certain pre-malignant and pre-invasive breast lesions to progress while others do not continues to perplex clinicians. Clinicians remain at a crossroads with effectively managing the high-risk patient subpopulation owing to the paucity of biomarkers that can adequately risk-stratify and inform clinical decisions that circumvent unnecessary administration of cytotoxic and invasive treatments. The...
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