Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered Plasma MicroRNA Expression in Patients with Mitral Chordae Tendineae Rupture.

The Journal of heart valve disease - 1 Sept 2016

Bulent Vatan Mehmet, Kalaycı Yigin Aysel, Akdemir Ramazan, Tarik Agac Mustafa, Akif Cakar Mehmet, Aksoy Murat, Tatli Ersan, Kilic Harun, Gunduz Huseyin, Guzel Derya, Karacan Keziban

Abstract excerpt

BACKGROUND: Mitral chordae tendineae rupture (MCTR) is a progressive disorder which leads to severe mitral regurgitation. Despite its importance, the precise pathogenetic mechanism of MCTR remains unclear. The study aim was to investigate the expression profile of circulating microRNAs (miRNAs) as being potentially involved in the development of MCTR. METHODS: Twenty-one patients with 'primary' MCTR, and 30 age-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Complementary
Share to TGFBR2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Heart Valve Diseases

Share to MicroRNAs

Share to Nucleic Acid Amplification Techniques

Share to Real-Time Polymerase Chain Reaction

Share to Rupture, Spontaneous

Source

Identifiers

PMID: 28238240

Genes

NRAS
TGFBR2
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered Plasma MicroRNA Expression in Patients with Mitral Chordae Tendineae Rupture.PMID 28238240Read ↗

Matrix metalloproteinase-1 mitral expression and -1607 1G/2G gene promoter polymorphism in mitral chordae tendinae rupture.Semantic proximity Read ↗

MicroRNAs in Valvular Heart Diseases: Biological Regulators, Prognostic Markers and Therapeutical TargetsSemantic proximity Read ↗

MicroRNAs in Valvular Heart Diseases: Biological Regulators, Prognostic Markers and Therapeutical TargetsSemantic proximity Read ↗

Matrix Metalloproteinases (MMPs), Their Genetic Variants and miRNA in Mitral Valve Diseases: Potential Biomarker Tools and Targets for Personalized Treatments.Semantic proximity Read ↗

Analysis of circulating microRNAs in patients with repaired Tetralogy of Fallot with and without heart failureSemantic proximity Read ↗

Comprehensive microRNA profiling reveals potential augmentation of the IL1 pathway in rheumatic heart valve diseaseSemantic proximity Read ↗

Selective MicroRNA Suppression in Human Thoracic AneurysmsSemantic proximity Read ↗

MicroRNA Expression Signature in Human Calcific Aortic Valve DiseaseSemantic proximity Read ↗

Altered MicroRNA Expression in Intracranial Aneurysmal Tissues: Possible Role in TGF-β Signaling PathwaySemantic proximity Read ↗

Mitral valve prolapse.Semantic proximity Read ↗

Atrial fibrillation alters the microRNA expression profiles of the left atria of patients with mitral stenosisSemantic proximity Read ↗

Characterization of Circulating MicroRNA Expression in Patients with a Ventricular Septal DefectSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.