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Article

Selective MicroRNA Suppression in Human Thoracic Aneurysms

19 Oct 2011

Abstract excerpt

BACKGROUND: Increasing evidence points to a direct role for altered microRNA (miRNA or miR) expression levels in cardiovascular remodeling and disease progression. Although alterations in miR expression levels have been directly linked to cardiac hypertrophy, fibrosis, and remodeling, their role in regulating gene expression during thoracic aortic aneurysm (TAA) development has yet to be explored. METHODS AND...

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PMID: 22010139
DOI: 10.1161/circgenetics.111.960419

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