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Comprehensive microRNA profiling reveals potential augmentation of the IL1 pathway in rheumatic heart valve disease

16 Mar 2018

Abstract excerpt

BACKGROUND: Valvular heart disease is a leading cause of cardiovascular mortality, especially in China. More than a half of valvular heart diseases are caused by acute rheumatic fever. microRNA is involved in many physiological and pathological processes. However, the miRNA profile of the rheumatic valvular heart disease is unknown. This research is to discuss microRNAs and their target gene pathways involved in...

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PMID: 29548280
DOI: 10.1186/s12872-018-0788-2

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