Article
C57BL/6 Substrains Exhibit Different Responses to Acute Carbon Tetrachloride Exposure: Implications for Work Involving Transgenic Mice.
Gene expression - 7 Jul 2017
McCracken Jennifer M, Chalise Prabhakar, Briley Shawn M, Dennis Katie L, Jiang Lu, Duncan Francesca E, Pritchard Michele T
Abstract excerpt
Biological differences exist between strains of laboratory mice, and it is becoming increasingly evident that there are differences between substrains. In the C57BL/6 mouse, the primary substrains are called 6J and 6N. Previous studies have demonstrated that 6J and 6N mice differ in response to many experimental models of human disease. The aim of our study was to determine if differences exist between 6J and 6N...
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