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Article

Airway gene expression of IL-1 pathway mediators predicts exacerbation risk in obstructive airway disease.

International journal of chronic obstructive pulmonary disease - 1 Jan 2017

Baines Katherine J, Fu Juan-Juan, McDonald Vanessa M, Gibson Peter G

Abstract excerpt

BACKGROUND: Exacerbations of asthma and COPD are a major cause of morbidity and mortality and are responsible for significant health care costs. This study further investigates interleukin (IL)-1 pathway activation and its relationship with exacerbations of asthma and COPD. METHODS: In this prospective cohort study, 95 participants with stable asthma (n=35) or COPD (n=60) were recruited and exacerbations recorded...

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Source

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Identifiers

PMID: 28223794
DOI: 10.2147/COPD.S119443
PMCID: PMC5308595

Genes

IRAK2
IRAK3
PELI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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