Article
Airway IL-1β and Systemic Inflammation as Predictors of Future Exacerbation Risk in Asthma and COPD.
Chest - 1 Sept 2015
Fu Juan-Juan, McDonald Vanessa M, Baines Katherine J, Gibson Peter G
Abstract excerpt
BACKGROUND: The innate inflammatory pathways involved in the frequent exacerbator phenotypes of asthma and COPD are not well understood. This study aimed to investigate airway innate immune activation and systemic inflammation as predictors of exacerbations in asthma and COPD. METHODS: In this prospective cohort study, baseline airway IL-1β, serum C-reactive protein, and IL-6 were assessed in 152 participants...
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