Article
[Polymorphism of osteoprotegerin gene and osteoporosis in postmenopausal women].
Ginekologia polska - 1 May 2009
Seremak-Mrozikiewicz Agnieszka, Tatuśko Joanna, Drews Krzysztof, Barlik Magdalena, Krajewski Paweł, Spaczyński Marek, Mrozikiewicz Przemysław M
Abstract excerpt
INTRODUCTION: Osteoprotegerin (OPG) plays a crucial role in the control of bone resorption through competitive inhibition of receptor activator of nuclear factor kappaB ligand (RANKL). This process leads to inhibition of osteoclasts differentiation and activity. The aim of the following study was to evaluate the distribution of genotypes of -163A>G and 1181G>C polymorphisms in OPG gene and analyze their...
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