Beta-thalassemia mutations in Rome. A high frequency of the IVSII-745 allele in subjects of latium origin.

Article

Beta-thalassemia mutations in Rome. A high frequency of the IVSII-745 allele in subjects of latium origin.

Haematologica - 1 Jan 2000

Massa A, Cianciulli P, Cianetti L, Iazzone R, Cenci A, Sorrentino F, Franco G, Pecci G, Papa G, Peschle C

Abstract excerpt

We studied the molecular bases of beta-thalassemia in Rome, a city centrally located in Latium, which is a region with a low incidence of beta-carriers. People also come to Rome from other regions for specific or prenatal diagnostic assessment. Only 11 patients (20%) out of 62 characterized beta-...

Topics

Alleles
Gene Frequency
Humans
Italy
Mutation
Rome
beta-Thalassemia

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