Article
Hb lepore/β0-thalassaemia with α+-thalassaemia interactions, a potential diagnostic pitfall.
The Malaysian journal of pathology - 1 Dec 2015
Alauddin Hafiza, Mohamad Nasir Suziana, Ahadon Madzlifah, Raja Sabudin Raja Zahratul Azma, Ithnin Azlin, Hussin Noor Hamidah, Alias Hamidah, Loh C-Khai, Abdul Latiff Zarina, Abdul Murad Nor Azian, Othman Ainoon
Abstract excerpt
Haemoglobin (Hb) Lepore is a variant Hb consisting of two α-globin and two δβ-globin chains. In a heterozygote, it is associated with clinical findings of thalassaemia minor, but interactions with other haemoglobinopathies can lead to various clinical phenotypes and pose diagnostic challenges. We reported a pair of siblings from a Malay family, who presented with pallor and hepatosplenomegaly at the ages of 21...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.