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Article

Extracellular Superoxide Dismutase Expression in Papillary Thyroid Cancer Mesenchymal Stem/Stromal Cells Modulates Cancer Cell Growth and Migration.

Scientific reports - 20 Feb 2017

Parascandolo Alessia, Rappa Francesca, Cappello Francesco, Kim Jaehyup, Cantu David A, Chen Herbert, Mazzoccoli Gianluigi, Hematti Peiman, Castellone Maria Domenica, Salvatore Marco, Laukkanen Mikko O

Abstract excerpt

Tumor stroma-secreted growth factors, cytokines, and reactive oxygen species (ROS) influence tumor development from early stages to the metastasis phase. Previous studies have demonstrated downregulation of ROS-producing extracellular superoxide dismutase (SOD3) in thyroid cancer cell lines although according to recent data, the expression of SOD3 at physiological levels stimulates normal and cancer cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28216675
DOI: 10.1038/srep41416
PMCID: PMC5316948

Genes

SOD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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