Article
Stromal modulation and its role in the diagnosis of papillary patterned thyroid lesions.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Daoud Sahar Aly, Esmail Reham Shehab El Nemr, Hareedy Amal Ahmed, Khalil Abdullah
Abstract excerpt
The papillary patterned lesion of thyroid may be challenging with many diagnostic pitfalls. Tumor stroma plays an important part in the determination of the tumor phenotype. CD34 is thought to be involved in the modulation of cell adhesion and signal transduction as CD34(+) fibrocytes are potent antigen-presenting cells. Smooth muscle actin (SMA) positivity could be diagnostic for fibroblast activation during...
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