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Pharmacogenomics: Relevance and opportunities for clinical pharmacology

29 Mar 2022

Abstract excerpt

Pharmacogenonomics (PGx) is the intersection of genomic medicine and pharmacology whereby knowledge of variation in an individual's genome is utilized to inform prescribing practice. The variation can affect genes responsible for determining either the pharmacokinetics or pharmacodynamics of a drug, and in some cases (for example, warfarin or phenytoin), response may be due to both pharmacokinetic and...

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PMID: 35347744
DOI: 10.1111/bcp.15329

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