Article
Clinical-Grade Isolated Human Kidney Perivascular Stromal Cells as an Organotypic Cell Source for Kidney Regenerative Medicine.
Stem cells translational medicine - 1 Feb 2017
Leuning Daniëlle G, Reinders Marlies E J, Li Joan, Peired Anna J, Lievers Ellen, de Boer Hetty C, Fibbe Willem E, Romagnani Paola, van Kooten Cees, Little Melissa H, Engelse Marten A, Rabelink Ton J
Abstract excerpt
Mesenchymal stromal cells (MSCs) are immunomodulatory and tissue homeostatic cells that have shown beneficial effects in kidney diseases and transplantation. Perivascular stromal cells (PSCs) identified within several different organs share characteristics of bone marrow-derived MSCs (BM-MSCs). These PSCs may also possess tissue-specific properties and play a role in local tissue homeostasis. We hypothesized that...
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