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Article

PKH(high) cells within clonal human nephrospheres provide a purified adult renal stem cell population.

Stem cell research - 1 Nov 2013

Bombelli Silvia, Zipeto Maria Anna, Torsello Barbara, Bovo Giorgio, Di Stefano Vitalba, Bugarin Cristina, Zordan Paola, Viganò Paolo, Cattoretti Giorgio, Strada Guido, Bianchi Cristina, Perego Roberto A

Abstract excerpt

The existence and identification of adult renal stem cells is a controversial issue. In this study, renal stem cells were identified from cultures of clonal human nephrospheres. The cultured nephrospheres exhibited the activation of stem cell pathways and contained cells at different levels of maturation. In each nephrosphere the presence of 1.12-1.25 cells mirroring stem cell properties was calculated. The...

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PMID: 24012544
DOI: 10.1016/j.scr.2013.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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