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Article

De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells

1 Aug 2022

Abstract excerpt

During development, nephron structures are derived from a SIX2+ stem cell population. After 36 weeks of gestation, these cells are exhausted, and no new nephrons are formed. We have previously described a non-invasive strategy to isolate and expand the native SIX2+ kidney stem cells from the urine of preterm neonates, named neonatal kidney stem/progenitor cells (nKSPC). Here, we investigated the safety and...

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PMID: 35913414
DOI: 10.1111/ajt.17164

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