Article
Evaluation of TNF-alpha gene (G308A) and MBL2 gene codon 54 polymorphisms in Turkish patients with tuberculosis.
Journal of infection and public health - 1 Jan 2000
Ceylan Esma, Karkucak Mutlu, Coban Hikmet, Karadag Mehmet, Yakut Tahsin
Abstract excerpt
OBJECTIVE: MBL acts as a binding protein that enables uptake of mycobacteria into macrophages. And, TNF-alpha is an important cytokine that is involved in control of mycobacterial infections both in-vivo and in-vitro. A large number of genetic factors exerting susceptibility to tuberculosis has been identified, among which mannose-binding lectin and tumor necrosis factor-alpha call attention. The objective of...
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