Article
Cyclin A2 is essential for mouse gonocyte maturation.
Cell cycle (Georgetown, Tex.) - 1 Jul 2020
Ma Fanhua, Wang Xiangyuan, Chung Sanny S W, Sicinski Piotr, Shang Enyuan, Wolgemuth Debra J
Abstract excerpt
In mammals, male gonocytes are derived from primordial germ cells during embryogenesis, enter a period of mitotic proliferation, and then become quiescent until birth. After birth, the gonocytes proliferate and migrate from the center of testicular cord toward the basement membrane to form the pool of spermatogonial stem cells (SSCs) and establish the SSC niche architecture. However, the molecular mechanisms...
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