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Article

Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila.

Development (Cambridge, England) - 1 Dec 2009

Chen Dongsheng, Wang Qi, Huang Haidong, Xia Laixin, Jiang Xiaoyong, Kan Lijuan, Sun Qinmiao, Chen Dahua

Abstract excerpt

Increasing evidence supports the idea that the regulation of stem cells requires both extrinsic and intrinsic mechanisms. However, much less is known about how intrinsic signals regulate the fate of stem cells. Studies on germline stem cells (GSCs) in the Drosophila ovary have provided novel insi...

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Identifiers

PMID: 19906849
DOI: 10.1242/dev.039032

Genes

APC
GSC
APC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19906849-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila.PMID 19906849Read ↗

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