Article
Association study between the TP53 Rs1042522G/C polymorphism and susceptibility to systemic lupus erythematosus in a Chinese Han population.
Rheumatology international - 1 Apr 2017
Yang Jie, Zhu Ji-Min, Wu Song, Li Jing, Wang Ming-Rui, Wang Ting-Ting, Lu Yu-Wei
Abstract excerpt
Tumour suppressor protein 53 (p53) plays a central role in apoptosis, cell proliferation and death. Previously studies found contribution of functional p53 Arg72Pro polymorphism (TP53 rs1042522G/C polymorphism) in the development of systemic lupus erythematosus (SLE) remains controversial. In this study, for the first time, we evaluated its association with SLE in a Chinese Han population. This case-control study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
