Article
A Cross-Validation Design Using Age and HLA Alleles for the Assessment of Clinical Schizophrenia Risk.
Clinical laboratory - 1 Feb 2017
Laiyu Song, Lei Zhang, Soufu Xie, Junting Xv, Jie Zhou, Hui Liu
Abstract excerpt
BACKGROUND: Schizophrenia (SCH) is a highly heritable disease that occurs mostly in young adults. Genetic factors usually play important roles in the onset of SCH. Human leukocyte antigen complex (HLA) genes are considered to be the important genetic predisposition factor and the genetic markers in SCH and other diseases. METHODS: To screen SCH-associated HLA alleles, alleles for HLA-DRB1 and HLA-DQB1 loci were...
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