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Article

Identification of biomarkers associated with metabolic cardiovascular disease using mRNA-SNP-miRNA regulatory network analysis.

BMC cardiovascular disorders - 23 Jul 2021

Fan Zhiyuan, Peng Wenjuan, Wang Zhiwen, Zhang Ling, Liu Kuo

Abstract excerpt

BACKGROUND: CVD is the leading cause of death in T2DM patients. However, few biomarkers have been identified to detect and diagnose CVD in the early stage of T2DM. The aim of our study was to identify the important mRNAs, micro (mi)RNAs and SNPs (single nucleotide polymorphisms) that are associated with metabolic cardiovascular disease. MATERIALS AND METHODS: Expression profiles and GWAS data were obtained from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34301176
DOI: 10.1186/s12872-021-02166-4
PMCID: PMC8305867

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