Article
Immunological evaluation of peptide vaccination for cancer patients with the HLA -A11+ or -A33+ allele.
Cancer science - 1 Apr 2017
Sakamoto Shinjiro, Matsueda Satoko, Takamori Shinzo, Toh Uhi, Noguchi Masanori, Yutani Shigeru, Yamada Akira, Shichijo Shigeki, Yamada Teppei, Suekane Shigetaka, Kawano Kouichiro, Naitou Masayasu, Sasada Tetsuro, Hattori Noboru, Kohno Nobuoki, Itoh Kyogo
Abstract excerpt
The HLA-A11 or -A33 allele is found in approximately 18% or 10% of the Asian population, respectively, but each of which is a minor allele worldwide, and therefore no clinical trials were previously conducted. To develop a therapeutic peptide vaccine for each of them, we investigated immunological responses of advanced cancer patients with the HLA-A11+ /A11+ (n = 18) or -A33+ /A33+ (n = 13) allele to personalized...
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