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Article

Capturing tumor heterogeneity and clonal evolution in solid cancers using circulating tumor DNA analysis.

Pharmacology & therapeutics - 1 Jun 2017

Perdigones Nieves, Murtaza Muhammed

Abstract excerpt

Circulating tumor DNA analysis has emerged as a potential noninvasive alternative to tissue biopsies for tumor genotyping in patients with metastatic cancer. This is particularly attractive in cases where tissue biopsies are contraindicated or repeat genotyping after progression on treatment is required. However, tissue and plasma analysis results are not always concordant and clinical interpretation of...

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Identifiers

PMID: 28167216
DOI: 10.1016/j.pharmthera.2017.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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